{"product_id":"new-product-566974","title":"Cleaved-Integrin  Alpha5 HC (F42) Polyclonal Antibody","description":"\u003cp\u003eThe product of ITGA5 belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.\u003c\/p\u003e\n\u003cp\u003eThe Cleaved-MMP-12 (G106) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and quantification of cleaved matrix metalloproteinase-12 (MMP-12) in various biological samples. This antibody has been meticulously developed using advanced immunization techniques, resulting in a high affinity and specificity towards the cleaved form of MMP-12.\u003cbr\u003e\u003cbr\u003eMatrix metalloproteinase-12, also known as macrophage elastase, plays a crucial role in tissue remodeling and inflammation. The cleaved form of MMP-12 is of particular interest as it is associated with various pathological conditions, including chronic obstructive pulmonary disease (COPD), emphysema, and atherosclerosis. Accurate detection and quantification of cleaved MMP-12 is essential for understanding the underlying mechanisms of these diseases and developing targeted therapeutic interventions.\u003cbr\u003e\u003cbr\u003eThe Cleaved-MMP-12 (G106) Polyclonal Antibody exhibits exceptional sensitivity and selectivity, enabling precise detection of cleaved MMP-12 even at low concentrations. It has been extensively validated for use in various immunoassays, including Western blotting, immunohistochemistry, and enzyme-linked immunosorbent assays (ELISA). This antibody demonstrates minimal cross-reactivity with other MMP isoforms, ensuring reliable and specific results.\u003cbr\u003e\u003cbr\u003eFurthermore, the Cleaved-MMP-12 (G106) Polyclonal Antibody is produced using high-quality materials and stringent quality control measures. Each batch is rigorously tested to ensure consistent performance, reliability, and reproducibility. The antibody is supplied in a convenient format, allowing for easy handling and storage.\u003cbr\u003e\u003cbr\u003eIn summary, the Cleaved-MMP-12 (G106) Polyclonal Antibody is a valuable tool for researchers and clinicians involved in studying MMP-12-related diseases. Its exceptional sensitivity, specificity, and reliability make it an indispensable asset for accurate detection and quantification of cleaved MMP-12 in various biological samples.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541229486360,"sku":"BT-AP01929","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_739593c6-80e4-4133-afbf-5f45b643cf9c.png?v=1705615757","url":"https:\/\/danabiosci.com\/products\/new-product-566974","provider":"Dana Bioscience","version":"1.0","type":"link"}