{"product_id":"new-product-566932","title":"Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody","description":"\u003cp\u003eCASP2 encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. Caspase 2 may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of CASP2 may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.\u003c\/p\u003e\n\u003cp\u003eThe Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection of cleaved caspase-2 p18 (G170) protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the cleaved caspase-2 p18 (G170) protein sequence. The resulting polyclonal antibody is purified using protein A affinity chromatography and validated for specificity and sensitivity using various techniques, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eThe Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody is suitable for use in a wide range of applications, including research studies investigating the role of caspase-2 in apoptosis and other cellular processes. This antibody is highly specific for the cleaved caspase-2 p18 (G170) protein and does not cross-react with other caspase family members or unrelated proteins. Additionally, this antibody exhibits high sensitivity, allowing for the detection of low levels of cleaved caspase-2 p18 (G170) protein in complex biological samples.\u003cbr\u003e\u003cbr\u003eIn summary, the Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody is a reliable and effective tool for the detection of cleaved caspase-2 p18 (G170) protein in various biological samples. Its high specificity and sensitivity make it an ideal choice for researchers investigating the role of caspase-2 in apoptosis and other cellular processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541220573464,"sku":"BT-AP01886","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_1905c427-1550-413b-b142-6c4319f921ae.png?v=1705615544","url":"https:\/\/danabiosci.com\/products\/new-product-566932","provider":"Dana Bioscience","version":"1.0","type":"link"}