{"product_id":"new-product-566830","title":"c-Fms Polyclonal Antibody","description":"\u003cp\u003eMacrophage colony-stimulating factor 1 receptor encoded by CSF1R is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1\/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\u003cp\u003eThe c-Fms Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of c-Fms protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human c-Fms protein. The resulting polyclonal antibody exhibits high affinity and specificity towards c-Fms protein, making it an ideal tool for various applications such as Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eThe c-Fms Polyclonal Antibody is validated for use in human, mouse, and rat samples, and has been extensively tested to ensure consistent and reliable results. This antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is recommended to store the antibody at -20°C for long-term storage and to avoid repeated freeze-thaw cycles.\u003cbr\u003e\u003cbr\u003eOverall, the c-Fms Polyclonal Antibody is a valuable tool for researchers studying the role of c-Fms protein in various biological processes, including cell differentiation, proliferation, and survival. Its high specificity and sensitivity make it an excellent choice for detecting c-Fms protein in complex biological samples.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541192458520,"sku":"BT-AP01721","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_b5c5f289-ad78-478f-8c7c-93fd6480be1e.png?v=1705614942","url":"https:\/\/danabiosci.com\/products\/new-product-566830","provider":"Dana Bioscience","version":"1.0","type":"link"}