{"product_id":"new-product-566813","title":"CEP57 Polyclonal Antibody","description":"\u003cp\u003eCEP57 (centrosomal protein 57) encodes a cytoplasmic protein called Translokin. This protein localizes to the centrosome and has a function in microtubular stabilization. The N-terminal half of this protein is required for its centrosome localization and for its multimerization, and the C-terminal half is required for nucleating, bundling and anchoring microtubules to the centrosomes. This protein specifically interacts with fibroblast growth factor 2 (FGF2), sorting nexin 6, Ran-binding protein M and the kinesins KIF3A and KIF3B, and thus mediates the nuclear translocation and mitogenic activity of the FGF2. It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells. This protein is crucial for maintaining correct chromosomal number during cell division. Mutations in CEP57 cause mosaic variegated aneuploidy syndrome, a rare autosomal recessive disorder. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.\u003c\/p\u003e\n\u003cp\u003eThe CEP57 Polyclonal Antibody is a highly reliable and efficient tool designed for the detection and analysis of CEP57 protein expression in various biological samples. This antibody is produced using advanced techniques, ensuring its high specificity and sensitivity.\u003cbr\u003e\u003cbr\u003eThe CEP57 Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It enables accurate and precise identification of CEP57 protein in different tissues and cell types, facilitating comprehensive research in the field of cell biology.\u003cbr\u003e\u003cbr\u003eWith its superior quality and performance, the CEP57 Polyclonal Antibody guarantees consistent and reproducible results, making it an indispensable asset for scientists and researchers engaged in studying the role and function of CEP57 protein in cellular processes. Its exceptional sensitivity allows for the detection of even low levels of CEP57 expression, ensuring accurate quantification and analysis.\u003cbr\u003e\u003cbr\u003eFurthermore, the CEP57 Polyclonal Antibody is manufactured under strict quality control measures, ensuring batch-to-batch consistency and reliability. It is supplied in a convenient and user-friendly format, facilitating easy handling and storage.\u003cbr\u003e\u003cbr\u003eIn summary, the CEP57 Polyclonal Antibody is a highly efficient and reliable tool that enables precise detection and analysis of CEP57 protein expression. Its exceptional sensitivity, specificity, and ease of use make it an invaluable asset for researchers in the field of cell biology.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541186068760,"sku":"BT-AP01699","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_63374ffb-48d4-4799-a615-097147cbdff4.png?v=1705614850","url":"https:\/\/danabiosci.com\/products\/new-product-566813","provider":"Dana Bioscience","version":"1.0","type":"link"}