{"product_id":"new-product-566806","title":"CEP135 Polyclonal Antibody","description":"\u003cp\u003eCEP135 (centrosomal protein 135) encodes a centrosomal protein, which acts as a scaffolding protein during early centriole biogenesis, and is also required for centriole-centriole cohesion during interphase. Mutations in CEP135 are associated with autosomal recessive primary microcephaly-8.\u003c\/p\u003e\n\u003cp\u003eThe Cdc16 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Cdc16 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human Cdc16 protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and is suitable for use in a variety of applications, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eThe Cdc16 protein is a key component of the anaphase-promoting complex\/cyclosome (APC\/C), which is a large multi-subunit E3 ubiquitin ligase that plays a critical role in regulating the cell cycle. Specifically, Cdc16 is involved in the activation of the APC\/C during mitosis, which leads to the degradation of key cell cycle regulators and the progression of the cell cycle. Dysregulation of the APC\/C has been implicated in a variety of human diseases, including cancer, making the Cdc16 Polyclonal Antibody a valuable tool for researchers studying the molecular mechanisms underlying these diseases.\u003cbr\u003e\u003cbr\u003eOverall, the Cdc16 Polyclonal Antibody is a high-quality research reagent that offers excellent sensitivity and specificity for the detection of Cdc16 protein in a variety of biological samples. Its use in a range of applications makes it a versatile tool for researchers studying the cell cycle and related processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541185184024,"sku":"BT-AP01692","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_b1caabe0-9921-48a0-9104-89c99d52e5be.png?v=1705614816","url":"https:\/\/danabiosci.com\/products\/new-product-566806","provider":"Dana Bioscience","version":"1.0","type":"link"}