{"product_id":"new-product-566803","title":"CENP-A Polyclonal Antibody","description":"\u003cp\u003eCentromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms.\u003c\/p\u003e\n\u003cp\u003eThe CENP-A Polyclonal Antibody is a highly specific and sensitive tool for the detection of centromere protein A (CENP-A) in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human CENP-A protein. The resulting polyclonal antibody exhibits high affinity and specificity towards CENP-A, making it an ideal reagent for various applications, including immunoblotting, immunoprecipitation, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eThe CENP-A Polyclonal Antibody is validated for use in human, mouse, and rat samples, and has been extensively tested for its performance in various experimental conditions. This antibody is supplied as a purified IgG fraction, and is suitable for use in both research and diagnostic applications.\u003cbr\u003e\u003cbr\u003eWith its high specificity and sensitivity, the CENP-A Polyclonal Antibody is an essential tool for researchers studying the role of CENP-A in various cellular processes, including chromosome segregation, mitosis, and cell division. Its reliable performance and consistent results make it a valuable addition to any laboratory working in the field of cell biology and molecular biology.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541184495896,"sku":"BT-AP01672","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_02aced65-c2b8-442c-a84a-89f93ad1c974.png?v=1705614800","url":"https:\/\/danabiosci.com\/products\/new-product-566803","provider":"Dana Bioscience","version":"1.0","type":"link"}