{"product_id":"new-product-566800","title":"CEL Polyclonal Antibody","description":"\u003cp\u003eThe carboxyl ester lipase encoded by CEL is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein.\u003c\/p\u003e\n\u003cp\u003eThe CEL Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of CEL protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human CEL protein. The resulting polyclonal antibody exhibits high affinity and specificity towards CEL protein, making it an ideal tool for various applications in research and diagnostics.\u003cbr\u003e\u003cbr\u003eThe CEL Polyclonal Antibody is purified using a combination of protein A and peptide affinity chromatography, ensuring high purity and minimal cross-reactivity with other proteins. This antibody is suitable for use in various immunoassays, including Western blotting, ELISA, immunohistochemistry, and flow cytometry. It has been validated for use in human, mouse, and rat samples, making it a versatile tool for researchers working with different animal models.\u003cbr\u003e\u003cbr\u003eThe CEL Polyclonal Antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is available in different sizes to meet the needs of different applications and budgets. This antibody is manufactured under strict quality control standards to ensure consistent performance and reproducibility.\u003cbr\u003e\u003cbr\u003eIn summary, the CEL Polyclonal Antibody is a reliable and high-quality reagent for the detection and quantification of CEL protein in various biological samples. Its high specificity, sensitivity, and versatility make it an essential tool for researchers and clinicians working in the fields of diabetes, obesity, and cardiovascular diseases.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541184266520,"sku":"BT-AP01669","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_bb2400c0-3426-4f5e-8121-5d41f53800e8.png?v=1705614783","url":"https:\/\/danabiosci.com\/products\/new-product-566800","provider":"Dana Bioscience","version":"1.0","type":"link"}