{"product_id":"new-product-566746","title":"Cdc25B Polyclonal Antibody","description":"\u003cp\u003eCDC25B (cell division cycle 25B) is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.\u003c\/p\u003e\n\u003cp\u003eThe Cdc25B Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Cdc25B protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human Cdc25B protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and is suitable for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eThe Cdc25B protein is a member of the Cdc25 family of dual-specificity phosphatases that play a critical role in cell cycle regulation. Specifically, Cdc25B is involved in the G2\/M transition of the cell cycle by activating cyclin-dependent kinases (CDKs) and promoting the entry of cells into mitosis. Dysregulation of Cdc25B expression or activity has been implicated in various human diseases, including cancer.\u003cbr\u003e\u003cbr\u003eThe Cdc25B Polyclonal Antibody has been extensively validated for its specificity and sensitivity in detecting Cdc25B protein in various cell lines and tissues. It has been shown to recognize both endogenous and recombinant Cdc25B protein with high affinity and specificity. This antibody is an essential tool for researchers studying the role of Cdc25B in cell cycle regulation and its potential as a therapeutic target for cancer and other diseases.\u003cbr\u003e\u003cbr\u003eIn summary, the Cdc25B Polyclonal Antibody is a high-quality research tool that offers reliable and accurate detection of Cdc25B protein in various biological samples. Its specificity and sensitivity make it an ideal choice for researchers studying the role of Cdc25B in cell cycle regulation and its potential as a therapeutic target.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541166670104,"sku":"BT-AP01581","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_4a492070-e7f6-4b0c-ad97-8de705ba9023.png?v=1705614470","url":"https:\/\/danabiosci.com\/products\/new-product-566746","provider":"Dana Bioscience","version":"1.0","type":"link"}