{"product_id":"new-product-566684","title":"CD5 Polyclonal Antibody","description":"\u003cp\u003eCD5 (also designated Lyt-1) has been identified as a transmembrane glycoprotein that is expressed on 70% of normal peripheral blood lymphocytes and on virtually all T lymphocytes in thymus and peripheral blood. Activation of T cells through the T cell receptor (TCR) results in tyrosine phosphorylation of CD5, and the absence of CD5 renders T cells hyper-responsive to TCR-mediated activation. CD5 associates with the TCR\/ CD3-z chain and with the Src family kinase Lck p56. In vitro studies have shown a 10- to 15-fold increase in the kinase activity of Lck bound to CD5. The B cell antigen, CD72, serves as a receptor for CD5. The consequence of CD5 binding to its cognate receptor is still in question and likely plays a role in thymic selection.\u003c\/p\u003e\n\u003cp\u003eThe CD5 Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and analysis of CD5 protein expression in various biological samples. This antibody is produced through a rigorous purification process, ensuring high purity and quality. It exhibits exceptional affinity and specificity towards CD5, a cell surface glycoprotein predominantly expressed on T lymphocytes and a subset of B lymphocytes. \u003cbr\u003e\u003cbr\u003eThe CD5 Polyclonal Antibody is suitable for a wide range of applications, including immunohistochemistry, immunofluorescence, flow cytometry, and western blotting. It enables researchers to investigate the role of CD5 in various physiological and pathological processes, such as immune response, autoimmunity, and lymphoproliferative disorders. \u003cbr\u003e\u003cbr\u003eWith its superior performance and reliability, this antibody provides accurate and reproducible results, making it an indispensable tool for both basic research and clinical diagnostics. It is supplied in a convenient and ready-to-use format, ensuring ease of use and minimizing experimental variability. \u003cbr\u003e\u003cbr\u003eChoose the CD5 Polyclonal Antibody for its exceptional sensitivity, specificity, and versatility, and unlock new insights into the intricate mechanisms of immune regulation and disease pathogenesis.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541142585624,"sku":"BT-AP01509","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_098cd667-83d4-4805-a650-085801b9d88a.png?v=1705614136","url":"https:\/\/danabiosci.com\/products\/new-product-566684","provider":"Dana Bioscience","version":"1.0","type":"link"}