{"product_id":"new-product-566541","title":"CCP2 Polyclonal Antibody","description":"\u003cp\u003eThe peptidase M14 family of carboxypeptidases (CPs) are involved in various functions throughout the body which include digestion of food and biosynthesis of peptides that function in intercellular signaling. CCP2 (cytosolic carboxypeptidase 2), also known as AGBL2 (ATP\/GTP binding protein-like 2), is a 902 amino acid cytoplasmic protein belonging to the peptidase M14 family. CCP2 is considered a metallocarboxypeptidase that may play a role in the processing of tubulin. CCP2 binds one zinc ion per subunit as a cofactor and exists as three alternatively spliced isoforms. The gene encoding CCP2 is located on human chromosome 11p11.2. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.\u003c\/p\u003e\n\u003cp\u003eThe CCP2 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and quantification of cyclic citrullinated peptide 2 (CCP2) in various biological samples. This antibody is produced through a rigorous process of immunization using a synthetic peptide corresponding to the CCP2 sequence, ensuring its high affinity and specificity towards the target antigen.\u003cbr\u003e\u003cbr\u003eThe CCP2 Polyclonal Antibody exhibits exceptional sensitivity, enabling the detection of even low levels of CCP2 in complex biological matrices. Its robust performance and minimal cross-reactivity with other related peptides make it an ideal choice for a wide range of applications, including enzyme-linked immunosorbent assays (ELISA), immunohistochemistry (IHC), and western blotting.\u003cbr\u003e\u003cbr\u003eThis antibody is manufactured under strict quality control measures, ensuring batch-to-batch consistency and reproducibility. It is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation steps. The CCP2 Polyclonal Antibody is compatible with various detection systems and can be used in both research and clinical settings.\u003cbr\u003e\u003cbr\u003eWith its exceptional specificity, sensitivity, and reliability, the CCP2 Polyclonal Antibody is an indispensable tool for researchers and clinicians studying autoimmune diseases, particularly rheumatoid arthritis. Its accurate and precise quantification of CCP2 levels in biological samples contributes to a deeper understanding of disease mechanisms and aids in the development of targeted therapies.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541080850712,"sku":"BT-AP01318","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_d48f5a78-db2e-4ca1-94dd-a27b3ed51c63.png?v=1705613350","url":"https:\/\/danabiosci.com\/products\/new-product-566541","provider":"Dana Bioscience","version":"1.0","type":"link"}