{"product_id":"new-product-566488","title":"Caspase-9 Polyclonal Antibody","description":"\u003cp\u003eCASP9 encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\u003cp\u003eThe Caspase-9 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Caspase-9 protein in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards the target protein.\u003cbr\u003e\u003cbr\u003eCaspase-9 is a crucial member of the caspase family, playing a pivotal role in the initiation of apoptosis, or programmed cell death. It is involved in the activation of downstream caspases, leading to the execution of apoptosis. Dysregulation of Caspase-9 has been implicated in various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases.\u003cbr\u003e\u003cbr\u003eThe Caspase-9 Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes both the pro-form and the active form of Caspase-9, enabling comprehensive analysis of its expression and activation status.\u003cbr\u003e\u003cbr\u003eThis antibody has been rigorously validated for its specificity and sensitivity, ensuring reliable and reproducible results. It exhibits minimal cross-reactivity with other caspase family members, ensuring accurate detection of Caspase-9 without interference from closely related proteins.\u003cbr\u003e\u003cbr\u003eThe Caspase-9 Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. It is provided in a convenient format, allowing for easy storage and handling.\u003cbr\u003e\u003cbr\u003eIn summary, the Caspase-9 Polyclonal Antibody is a highly reliable and efficient tool for the detection and quantification of Caspase-9 protein. Its exceptional specificity, sensitivity, and versatility make it an invaluable asset for researchers and clinicians studying apoptosis and its implications in various diseases.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541066629400,"sku":"BT-AP01212","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_f6ca1256-4f17-4714-82b2-e24ef9662006.png?v=1705613073","url":"https:\/\/danabiosci.com\/products\/new-product-566488","provider":"Dana Bioscience","version":"1.0","type":"link"}