{"product_id":"new-product-566304","title":"BMP-8 Polyclonal Antibody","description":"\u003cp\u003eBMP8B (bone morphogenetic protein 8b) encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of BMP8B may be downregulated in pancreatic cancer. BMP8B may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1.\u003c\/p\u003e\n\u003cp\u003eThe BMP-8 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of BMP-8 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human BMP-8 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards BMP-8 protein, making it an ideal tool for various research applications.\u003cbr\u003e\u003cbr\u003eThe BMP-8 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various assays, including Western blotting, immunohistochemistry, and ELISA. It has been shown to detect BMP-8 protein in a variety of tissues and cell types, including bone, cartilage, muscle, and adipose tissue. This antibody has also been used to study the role of BMP-8 in various physiological and pathological processes, such as bone formation, muscle regeneration, and cancer.\u003cbr\u003e\u003cbr\u003eThe BMP-8 Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified from rabbit serum. It is provided in a liquid form, which can be easily diluted and used for various applications. This antibody is suitable for use in both research and diagnostic applications, and it is compatible with a wide range of detection systems.\u003cbr\u003e\u003cbr\u003eIn summary, the BMP-8 Polyclonal Antibody is a highly specific and sensitive antibody that is ideal for the detection of BMP-8 protein in various biological samples. It has been extensively validated for its specificity and sensitivity, and it is suitable for use in various research and diagnostic applications.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47541011480856,"sku":"BT-AP00931","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_53f9dd68-31b4-4fe7-b378-1b1e7646f145.png?v=1705612048","url":"https:\/\/danabiosci.com\/products\/new-product-566304","provider":"Dana Bioscience","version":"1.0","type":"link"}