{"product_id":"new-product-566233","title":"Bag-3 Polyclonal Antibody","description":"\u003cp\u003eBAG proteins compete with Hip for binding to the Hsc70\/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.\u003c\/p\u003e\n\u003cp\u003eThe Bag-3 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Bag-3 protein expression in various biological samples. This antibody is produced using state-of-the-art technology, ensuring exceptional quality and performance.\u003cbr\u003e\u003cbr\u003eBag-3, also known as Bcl-2-associated athanogene 3, is a multifunctional protein involved in diverse cellular processes, including apoptosis, autophagy, and cell migration. It plays a crucial role in maintaining cellular homeostasis and has been implicated in various diseases, such as cancer and neurodegenerative disorders.\u003cbr\u003e\u003cbr\u003eThe Bag-3 Polyclonal Antibody exhibits excellent sensitivity and specificity, enabling accurate and precise detection of Bag-3 protein levels. It has been extensively validated in a wide range of experimental settings, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a ready-to-use format, eliminating the need for time-consuming preparation steps. The Bag-3 Polyclonal Antibody is compatible with various detection methods and can be used in both research and clinical applications.\u003cbr\u003e\u003cbr\u003eWith its exceptional performance and reliability, the Bag-3 Polyclonal Antibody is an indispensable tool for scientists and researchers studying Bag-3 protein function and its involvement in disease processes. Its high specificity and sensitivity make it an ideal choice for accurate and reproducible results in a wide range of experimental techniques.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47540987658520,"sku":"BT-AP00819","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_d196f314-42c5-48d8-b930-b9d1d7b28d84.png?v=1705611668","url":"https:\/\/danabiosci.com\/products\/new-product-566233","provider":"Dana Bioscience","version":"1.0","type":"link"}