{"product_id":"new-product-566201","title":"ATP7A Polyclonal Antibody","description":"\u003cp\u003eATP7A (ATPase copper transporting alpha) encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway.\u003c\/p\u003e\n\u003cp\u003eIt relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in ATP7A are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed.\u003c\/p\u003e\n\u003cp\u003eThe ATP7A Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of ATP7A protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human ATP7A protein.\u003c\/p\u003e\n\u003cp\u003eThe ATP7A Polyclonal Antibody has been extensively validated for its specificity and sensitivity in Western blotting, immunohistochemistry, and immunofluorescence applications. This antibody is suitable for use in a wide range of research applications, including studies of copper metabolism, Menkes disease, and Wilson's disease. The ATP7A Polyclonal Antibody is supplied as a purified IgG fraction, and is available in various sizes to meet the needs of different research projects.\u003c\/p\u003e\n\u003cp\u003eWith its high specificity and sensitivity, the ATP7A Polyclonal Antibody is an essential tool for researchers studying copper transport and related diseases.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47540979859736,"sku":"BT-AP00747","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_5db9fb2a-42b1-4210-88d5-ae2318608a28.png?v=1705611522","url":"https:\/\/danabiosci.com\/products\/new-product-566201","provider":"Dana Bioscience","version":"1.0","type":"link"}