{"product_id":"new-product-565854","title":"Actinin-Alpha2\/3 Polyclonal Antibody","description":"\u003cp\u003eAlpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. ACTN2 encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for ACTN2.\u003c\/p\u003e\n\u003cp\u003eThe Actinin-Alpha2\/3 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Actinin-Alpha2 and Actinin-Alpha3 proteins. This antibody is produced through a rigorous process, ensuring its high affinity and sensitivity towards the target proteins.\u003cbr\u003e\u003cbr\u003eActinin-Alpha2 and Actinin-Alpha3 are members of the actin-binding protein family, playing crucial roles in the organization and stabilization of the cytoskeleton. They are involved in various cellular processes, including cell adhesion, migration, and contraction. The Actinin-Alpha2\/3 Polyclonal Antibody enables researchers to investigate the expression, localization, and function of these proteins in a wide range of biological samples.\u003cbr\u003e\u003cbr\u003eThis antibody exhibits exceptional performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes both endogenous and recombinant Actinin-Alpha2 and Actinin-Alpha3 proteins, providing accurate and reproducible results. The Actinin-Alpha2\/3 Polyclonal Antibody is compatible with multiple species, making it suitable for diverse experimental settings.\u003cbr\u003e\u003cbr\u003eWith its high specificity and sensitivity, this antibody offers researchers a valuable tool for studying Actinin-Alpha2 and Actinin-Alpha3 proteins in different biological contexts. Its reliable performance and versatility make it an indispensable asset for investigations in cell biology, developmental biology, and disease research.\u003cbr\u003e\u003cbr\u003eThe Actinin-Alpha2\/3 Polyclonal Antibody is supplied in a convenient format, ensuring ease of use and storage. It is manufactured under strict quality control standards, guaranteeing batch-to-batch consistency and reliability. Researchers can trust in the quality and performance of this antibody to advance their scientific endeavors and gain deeper insights into the functions of Actinin-Alpha2 and Actinin-Alpha3 proteins.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47540862845208,"sku":"BT-AP00217","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_92f4f29e-1571-46ce-aa03-696c2914cc9a.png?v=1705609813","url":"https:\/\/danabiosci.com\/products\/new-product-565854","provider":"Dana Bioscience","version":"1.0","type":"link"}