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ELK Biotechnology

SKU:ES3939

Calbindin D28K Rabbit Polyclonal Antibody

Calbindin D28K Rabbit Polyclonal Antibody

Regular price $248.00 USD
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Calbindin D28K Rabbit Polyclonal Antibody

Overview

Product name: Calbindin D28K rabbit pAb
Alternative Names: CALB1; CAB27; Calbindin; Calbindin D28; D-28K; Vitamin D-dependent calcium-binding protein, avian-type
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human CALB1. AA range:191-240
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 30kD
GeneID(Human): 793
Human Swiss-Prot No: P05937
Cellular localization: nucleus,cytosol,axon,dendrite,neuronal cell body,terminal bouton,synapse,extracellular exosome,
Background: The protein encoded by this gene is a member of the calcium-binding protein superfamily that includes calmodulin and troponin C. Originally described as a 27 kDa protein, it is now known to be a 28 kDa protein. It contains four active calcium-binding domains, and has two modified domains that are thought to have lost their calcium binding capability. This protein is thought to buffer entry of calcium upon stimulation of glutamate receptors. Depletion of this protein was noted in patients with Huntington disease. [provided by RefSeq, Jan 2015],
Species Reactivity: Human;Mouse;Rat
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