{"product_id":"new-product-381964","title":"Cleaved-Integrin α5 LC (E895) Rabbit Polyclonal Antibody","description":"\u003cp\u003eCleaved-Integrin α5 LC (E895) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\u003cdiv class=\"item item1\"\u003e\n\u003ch4 class=\"tit clearfix tabs\"\u003e\u003cspan class=\"fz20 fl tran300 active\"\u003eOverview\u003c\/span\u003e\u003c\/h4\u003e\n\u003cdiv class=\"cont fz16 pageStyle\"\u003e\n\u003cdiv id=\"tabs-container\" class=\"container1 swiper-container-horizontal swiper-container-autoheight\"\u003e\n\u003cdiv class=\"swiper-wrapper\"\u003e\n\u003cdiv class=\"swiper-slide pageStyle fz16 swiper-no-swiping swiper-slide-active\"\u003e\n\u003ctable class=\"table2\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"208px\" class=\"fz18\"\u003eProduct name:\u003c\/td\u003e\n\u003ctd\u003eCleaved-Integrin α5 LC (E895) rabbit pAb\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"fz18\"\u003eAlternative Names:\u003c\/td\u003e\n\u003ctd\u003eITGA5; FNRA; Integrin alpha-5; CD49 antigen-like family member E; Fibronectin receptor subunit alpha; Integrin alpha-F; VLA-5; CD antigen CD49e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"fz18\"\u003eApplications:\u003c\/td\u003e\n\u003ctd\u003eWB;ELISA\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"fz18\"\u003eRecommended Dilutions:\u003c\/td\u003e\n\u003ctd\u003eWestern Blot: 1\/500 - 1\/2000. ELISA: 1\/20000. Not yet tested in other applications.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"fz18\"\u003eImmunogen:\u003c\/td\u003e\n\u003ctd\u003eThe antiserum was produced against synthesized peptide derived from human ITGA5. AA range:876-925\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"fz18\"\u003eStorage:\u003c\/td\u003e\n\u003ctd\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"fz18\"\u003eStorage:\u003c\/td\u003e\n\u003ctd\u003e-20°C\/1 year\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"fz18\"\u003eClonality:\u003c\/td\u003e\n\u003ctd\u003ePolyclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"fz18\"\u003eIsotype:\u003c\/td\u003e\n\u003ctd\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"fz18\"\u003eConcentration:\u003c\/td\u003e\n\u003ctd\u003e1 mg\/ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"fz18\"\u003eObserved Band:\u003c\/td\u003e\n\u003ctd\u003e18kD\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"fz18\"\u003eGeneID（Human）:\u003c\/td\u003e\n\u003ctd\u003e3678\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"fz18\"\u003eHuman Swiss-Prot No:\u003c\/td\u003e\n\u003ctd\u003eP08648\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"fz18\"\u003eCellular localization:\u003c\/td\u003e\n\u003ctd\u003eMembrane; Single-pass type I membrane protein. Cell junction, focal adhesion . Cell surface .\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"fz18\"\u003eBackground:\u003c\/td\u003e\n\u003ctd\u003eintegrin subunit alpha 5(ITGA5) Homo sapiens The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015],\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"fz18\"\u003eSpecies Reactivity:\u003c\/td\u003e\n\u003ctd\u003eHuman;Rat;Mouse;\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"item item5\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca class=\"scaleimg\"\u003e\n\u003cdiv class=\"pic\"\u003e\u003cimg class=\"tran500\" alt=\"\" src=\"https:\/\/www.elkbiotech.com\/upload\/image\/Antibodies\/pAb\/ES1062-c-1.jpg\"\u003e\u003c\/div\u003e\n\u003cdiv class=\"text fz16\"\u003eWestern Blot analysis of various cells using Cleaved-Integrin α5 LC (E895) Polyclonal Antibody\u003c\/div\u003e\n\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca class=\"scaleimg\"\u003e\n\u003cdiv class=\"pic\"\u003e\u003cimg class=\"tran500\" alt=\"\" src=\"https:\/\/www.elkbiotech.com\/upload\/image\/Antibodies\/pAb\/ES1062-c-2.jpg\"\u003e\u003c\/div\u003e\n\u003cdiv class=\"text fz16\"\u003eWestern blot analysis of lysates from 293 and A549 cells, treated with etoposide 25uM 1h, using ITGA5 (light chain,Cleaved-Glu895) Antibody. The lane on the right is blocked with the synthesized peptide.\u003c\/div\u003e\n\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"ELK Biotechnology","offers":[{"title":"100ul","offer_id":47443494764824,"sku":"ES1062","price":248.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/ELK_047c8ab4-eb36-429f-be6d-66a52e012282.jpg?v=1704281414","url":"https:\/\/danabiosci.com\/products\/new-product-381964","provider":"Dana Bioscience","version":"1.0","type":"link"}