{"product_id":"new-product-340616","title":"CD1a Cortical Thymocytes","description":"\u003cp\u003eAt least five CD1 genes (CD1a, b, c, d, and e) are identified. Cd1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class I related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma\/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5, anti-CD1 is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1\/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. Anti-CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa).\u003c\/p\u003e","brand":"Dbiosys","offers":[{"title":"1ml \/ DBMM1","offer_id":47433568583960,"sku":"Mob363","price":725.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/TS104ACD1a.jpg?v=1704035025","url":"https:\/\/danabiosci.com\/products\/new-product-340616","provider":"Dana Bioscience","version":"1.0","type":"link"}