{"product_id":"new-product-340487","title":"Galectin-3","description":"\u003cp\u003eGalectins are a family of soluble β-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. The galectin-3 protein, also known as Mac-2, hMac-2, GALBP, CBP35 or LGALS3, contains a single carbohydrate binding domain, which binds galactose-containing glycoconjugates. Galectin-3 is expressed in colonic and intestinal epithelium, inflammatory macrophages, papillary and follicular carcinomas, neoplastic astrocytes and some B and T lymphocytes. Upregulated expression of galectin-3 is involved in cancer progression and metastasis. Galectin-3 mediates the endocytosis of β1 Integrins in a lactose-dependent manner and is associated with thyroid malignancy and Crohn’s disease. It may also be used as a marker for diagnosing casesinvolving Hurthle cell adenomas and carcinomas.\u003c\/p\u003e","brand":"Dbiosys","offers":[{"title":"1ml \/ 2B11+PD7\/26","offer_id":47433535717656,"sku":"Mob541","price":646.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/Galectin-3-1.jpg?v=1704034498","url":"https:\/\/danabiosci.com\/products\/new-product-340487","provider":"Dana Bioscience","version":"1.0","type":"link"}