{"product_id":"new-product-326492","title":"Anti-TGFBR2 antibody(DMC467), IgG1 Chimeric mAb","description":"\u003cdiv data-mce-fragment=\"1\" class=\"product-section\"\u003e\n\u003cdiv data-mce-fragment=\"1\" class=\"row\"\u003e\n\u003cdiv data-mce-fragment=\"1\" class=\"large-10 col pb-0 mb-0\"\u003e\n\u003cdiv data-mce-fragment=\"1\" class=\"panel entry-content\"\u003e\n\u003cp\u003e\u003cstrong\u003ePRODUCT DATA \u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable data-mce-fragment=\"1\" class=\"woocommerce-product-attributes shop_attributes\"\u003e\n\u003ctbody data-mce-fragment=\"1\"\u003e\n\u003ctr data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item woocommerce-product-attributes-item--attribute_pa_target\"\u003e\n\u003cth data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__label\"\u003eTARGET\u003c\/th\u003e\n\u003ctd data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__value\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003ca data-mce-fragment=\"1\" rel=\"tag\" href=\"https:\/\/www.dimabio.com\/target\/tgfbr2\" data-mce-href=\"https:\/\/www.dimabio.com\/target\/tgfbr2\"\u003eTGFBR2\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item woocommerce-product-attributes-item--attribute_synonyms\"\u003e\n\u003cth data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__label\"\u003eSYNONYMS\u003c\/th\u003e\n\u003ctd data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__value\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eAAT3; FAA3; LDS1B; LDS2; LDS2B; MFS2; RIIC; TAAD2; TBR-ii; TBRII; TGFbeta-RII; TGFR-2\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item woocommerce-product-attributes-item--attribute_pa_host-species\"\u003e\n\u003cth data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__label\"\u003eHOST SPECIES\u003c\/th\u003e\n\u003ctd data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__value\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eRabbit\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item woocommerce-product-attributes-item--attribute_description\"\u003e\n\u003cth data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__label\"\u003eDESCRIPTION\u003c\/th\u003e\n\u003ctd data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__value\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eAnti-TGFBR2 antibody(DMC467); IgG1 Chimeric mAb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item woocommerce-product-attributes-item--attribute_delivery\"\u003e\n\u003cth data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__label\"\u003eDELIVERY\u003c\/th\u003e\n\u003ctd data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__value\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eIn Stock\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item woocommerce-product-attributes-item--attribute_pa_uniprot-id\"\u003e\n\u003cth data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__label\"\u003eUNIPROT ID\u003c\/th\u003e\n\u003ctd data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__value\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eP37173\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item woocommerce-product-attributes-item--attribute_pa_igg-type\"\u003e\n\u003cth data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__label\"\u003eIGG TYPE\u003c\/th\u003e\n\u003ctd data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__value\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eRabbit:Human Fc chimeric IgG1\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item woocommerce-product-attributes-item--attribute_pa_clonality\"\u003e\n\u003cth data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__label\"\u003eCLONALITY\u003c\/th\u003e\n\u003ctd data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__value\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eMonoclonal\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item woocommerce-product-attributes-item--attribute_pa_reactivity\"\u003e\n\u003cth data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__label\"\u003eREACTIVITY\u003c\/th\u003e\n\u003ctd data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__value\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eHuman\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item woocommerce-product-attributes-item--attribute_pa_applications\"\u003e\n\u003cth data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__label\"\u003eAPPLICATIONS\u003c\/th\u003e\n\u003ctd data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__value\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eFlow Cyt\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item woocommerce-product-attributes-item--attribute_pa_recommended-dilutions\"\u003e\n\u003cth data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__label\"\u003eRECOMMENDED DILUTIONS\u003c\/th\u003e\n\u003ctd data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__value\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eFlow Cyt 1:100\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item woocommerce-product-attributes-item--attribute_pa_purification\"\u003e\n\u003cth data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__label\"\u003ePURIFICATION\u003c\/th\u003e\n\u003ctd data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__value\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003ePurified from cell culture supernatant by affinity chromatography\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item woocommerce-product-attributes-item--attribute_pa_formulation-reconstitution\"\u003e\n\u003cth data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__label\"\u003eFORMULATION \u0026amp; RECONSTITUTION\u003c\/th\u003e\n\u003ctd data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__value\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eLyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item woocommerce-product-attributes-item--attribute_storage-shipping\"\u003e\n\u003cth data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__label\"\u003eSTORAGE \u0026amp; SHIPPING\u003c\/th\u003e\n\u003ctd data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__value\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eStore at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item woocommerce-product-attributes-item--attribute_background\"\u003e\n\u003cth data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__label\"\u003eBACKGROUND\u003c\/th\u003e\n\u003ctd data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__value\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eThe protein encoded by this gene is a transmembrane protein that has a protein kinase domain; forms a heterodimeric complex with TGF-beta receptor type-1; and binds TGF-beta. This receptor:ligand complex phosphorylates proteins; which then enter the nucleus and regulate the transcription of genes related to cell proliferation; cell cycle arrest; wound healing; immunosuppression; and tumorigenesis. Mutations in this gene have been associated with Marfan Syndrome; Loeys-Deitz Aortic Aneurysm Syndrome; and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq; Aug 2017]\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item woocommerce-product-attributes-item--attribute_pa_usage\"\u003e\n\u003cth data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__label\"\u003eUSAGE\u003c\/th\u003e\n\u003ctd data-mce-fragment=\"1\" class=\"woocommerce-product-attributes-item__value\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eResearch use only\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv data-mce-fragment=\"1\" class=\"product-section\"\u003e\n\u003cdiv data-mce-fragment=\"1\" class=\"row\"\u003e\n\u003cdiv data-mce-fragment=\"1\" class=\"large-10 col pb-0 mb-0\"\u003e\n\u003cdiv data-mce-fragment=\"1\" class=\"large-8 col pb-0 mb-0\"\u003e\n\u003ch5 data-mce-fragment=\"1\" class=\"uppercase mt\"\u003eIMAGES\u003c\/h5\u003e\n\u003c\/div\u003e\n\u003cdiv data-mce-fragment=\"1\" class=\"panel entry-content\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cimg data-mce-fragment=\"1\" loading=\"eager\" sizes=\"(max-width: 399px) 100vw, 399px\" data-lazy-loaded=\"1\" srcset=\"https:\/\/www.dimabio.com\/wp-content\/uploads\/products\/antibody\/DMC100467-TGFBR2-Fig.1-FC-1-399x400.jpg 399w, https:\/\/www.dimabio.com\/wp-content\/uploads\/products\/antibody\/DMC100467-TGFBR2-Fig.1-FC-1-100x100.jpg 100w, https:\/\/www.dimabio.com\/wp-content\/uploads\/products\/antibody\/DMC100467-TGFBR2-Fig.1-FC-1-64x64.jpg 64w, https:\/\/www.dimabio.com\/wp-content\/uploads\/products\/antibody\/DMC100467-TGFBR2-Fig.1-FC-1-280x280.jpg 280w, https:\/\/www.dimabio.com\/wp-content\/uploads\/products\/antibody\/DMC100467-TGFBR2-Fig.1-FC-1.jpg 591w\" class=\"alignnone size-medium wp-image-7918 jetpack-lazy-image jetpack-lazy-image--handled\" height=\"400\" width=\"399\" alt=\"antibody-DMC100467 TGFBR2 Fig.1 FC 1\" src=\"https:\/\/www.dimabio.com\/wp-content\/uploads\/products\/antibody\/DMC100467-TGFBR2-Fig.1-FC-1-399x400.jpg\" decoding=\"async\" fetchpriority=\"high\" data-mce-src=\"https:\/\/www.dimabio.com\/wp-content\/uploads\/products\/antibody\/DMC100467-TGFBR2-Fig.1-FC-1-399x400.jpg\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eFigure 1. Flow cytometry analysis with Anti-TGFBR2 (DMC467) on Expi293 cells transfected with human TGFBR2 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Dima Biotech","offers":[{"title":"100 μg \/ Flow Cyt 1:100 \/ Monoclonal","offer_id":47431107477784,"sku":"DMC100467","price":438.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/Dimabio_e827b399-5888-44ea-9247-b0a5ec647dac.png?v=1703966398","url":"https:\/\/danabiosci.com\/products\/new-product-326492","provider":"Dana Bioscience","version":"1.0","type":"link"}