{"product_id":"new-product-285130","title":"CD161 polyclonal antibody","description":"\u003cp\u003ePlays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase\/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1\/PKB and RPS6KA1\/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N-acetyllactosamine epitope. Binds also to CLEC2D\/LLT1 as a ligand and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Rat,Mouse,Human","offer_id":45810726404376,"sku":"ABCBW13220","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_fd85b3ad-91f2-43b0-85a4-a43feb1f85d9.png?v=1689763261","url":"https:\/\/danabiosci.com\/products\/new-product-285130","provider":"Dana Bioscience","version":"1.0","type":"link"}