{"product_id":"new-product-284916","title":"Catenin delta 1 monoclonal antibody","description":"\u003cp\u003eCatenin δ-1 (p120 catenin) has an amino-terminal coiled-coil domain followed by a regulatory domain containing multiple phosphorylation sites and a central Armadillo repeat domain of ten linked 42-amino acid repeats. The carboxy-terminal tail has no known function . Catenin δ-1 fulfills critical roles in the regulation of cell-cell adhesion as it regulates E-cadherin turnover at the cell surface to determine the level of E-cadherin available for cell-cell adhesion . Catenin δ-1 has both positive and negative effects on cadherin-mediated adhesion . Actin dynamics are also regulated by catenin δ-1, which modulates RhoA, Rac, and cdc42 proteins . Analogous to β-catenin, catenin δ-1 translocates to the nucleus, although its role at this location is unclear. Many studies show that catenin δ-1 is expressed irregularly or is absent in various types of tumor cells, suggesting that catenin δ-1 may function as a tumor suppressor\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Mouse \/ Human","offer_id":45810421563672,"sku":"ABCBW13006","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_582fe6cb-a139-4c1c-a1c3-b5950f3ccfd6.png?v=1689762741","url":"https:\/\/danabiosci.com\/products\/new-product-284916","provider":"Dana Bioscience","version":"1.0","type":"link"}