{"product_id":"new-product-284830","title":"CD105 monoclonal antibody","description":"\u003cp\u003eCD105\/Endoglin is an auxiliary receptor for the TGF-β receptor complex, functioning in related signaling pathways . CD105\/Endoglin is a transmembrane protein that exists as a disulfide-linked homodimer. It is mainly expressed in vascular and connective tissues and in endothelial and stromal cells. Upregulated CD105\/endoglin expression has been reported during wound healing and tumor vascularization, and in inflammatory tissues and developing embryos . Mutations in CD105\/endoglin have been found to be a causal factor of hereditary hemorrhagic telangiectasia (HHT), a disease characterized by malformation of vascular structure . The importance of this protein for normal and tumor vascular function makes it a good marker for endothelial cell proliferation as well as a potential therapeutic target in cancer.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Mouse \/ Human","offer_id":45810303664408,"sku":"ABCBW12920","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_95a36094-482c-4584-bfe9-83aa53e3bdb8.png?v=1689762535","url":"https:\/\/danabiosci.com\/products\/new-product-284830","provider":"Dana Bioscience","version":"1.0","type":"link"}