{"product_id":"new-product-284816","title":"SOX9 monoclonal antibody","description":"\u003cp\u003eSox9 is a transcription factor with an HMG-box DNA binding domain that has homology to the HMG domain of the mammalian testis-determining factor, SRY . Sox9 regulates several important processes during embryonic development including chondrogenesis, during which it contributes to skeletal formation and digit specification . Sox9 also coordinates with steroidogenic factor-1 to direct Sertoli cell-specific expression of anti-Mullerian hormone during embryogenesis, thereby contributing to male sex determination . In addition, Sox9 is reportedly involved in the maintenance of adult stem cell populations, including multipotent neural stem cells , hair follicle stem cells , and mammary stem cells . Recent interest has focused on the role of Sox9 in tumor biology. For example, research studies have shown that Sox9 expression in lung adenocarcinoma induces a mesenchymal phenotype in tumor cells. Other research studies have shown that YAP1 induced upregulation of Sox9 confers cancer stem cell like properties on esophageal cancer cells . Moreover, Sox9 expression has been linked with several other tumor types including ovarian, prostate, and pancreatic malignancies .\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Mouse \/ Human","offer_id":45810291474712,"sku":"ABCBW12906","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_24f12455-bdf7-417a-8b7c-86ae9171599d.png?v=1689762506","url":"https:\/\/danabiosci.com\/products\/new-product-284816","provider":"Dana Bioscience","version":"1.0","type":"link"}