{"product_id":"new-product-284704","title":"BOB1 monoclonal antibody","description":"\u003cp\u003eB cell Oct binding factor-1 (BOB-1\/OBF-1) is a B cell restricted transcriptional coactivator. BOB-1 facilitates transactivation of immunoglobulins and other B cell specific genes through the binding and activation of the transcription factors Oct-1 and Oct-2 . Research studies have demonstrated that BOB-1 expression is required for antigen-dependent B cell maturation. In pathological conditions such as classical Hodgkin disease, loss of BOB-1 expression is thought, in part, to contribute to the defect in immunoglobulin gene expression by Hodgkin and Reed Sternberg cells. In the context of multiple myeloma, overexpression of BOB-1 has been shown to contribute to malignant plasma cell growth, in part, through enhanced transactivation of TNFRSF17\/BCMA.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Mouse \/ Human","offer_id":45810164498712,"sku":"ABCBW12794","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_e627ef04-47d7-4e0b-a23e-be287ce2d98a.png?v=1689762246","url":"https:\/\/danabiosci.com\/products\/new-product-284704","provider":"Dana Bioscience","version":"1.0","type":"link"}