{"product_id":"new-product-284618","title":"HIF1 beta monoclonal antibody","description":"\u003cp\u003eRequired for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens (By similarity).\u003cbr\u003e\nThe heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia (PubMed:26245371, PubMed:27782878).\u003cbr\u003e\nThe heterodimer ARNT:AHR binds to core DNA sequence 5'-TGCGTG-3' within the dioxin response element (DRE) of target gene promoters and activates their transcription (PubMed:28602820).\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Mouse \/ Mouse","offer_id":45810034966808,"sku":"ABCBW12708","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_4698a02f-5ce8-4dc8-b7a2-45670a806eba.png?v=1689762007","url":"https:\/\/danabiosci.com\/products\/new-product-284618","provider":"Dana Bioscience","version":"1.0","type":"link"}