{"product_id":"new-product-284489","title":"CD86 monoclonal antibody","description":"\u003cp\u003eCD80 (B7-1, BB1) and CD86 (B7-2, B70) are members of the B7 family of cell surface ligands that regulate T cell activation and immune responses. CD80 is expressed on activated antigen presenting cells, including dendritic cells, B cells, monocytes, and macrophages. CD86 is expressed on resting monocytes, dendritic cells, activated B lymphocytes, and can be further upregulated in the presence of inflammation. CD80 and CD86 are ligands for CD28, which functions as a T cell costimulatory receptor. Interaction of CD28 with CD80 or CD86 provides the second signal required for naïve T cell activation, T cell proliferation, and acquisition of effector functions. Alternatively, CD80 and CD86 also act as ligands to CTLA-4, which results in the downregulation of T cell activity.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Mouse \/ Human","offer_id":45809872077080,"sku":"ABCBW12579","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_b9aebde9-d557-4d87-a7e8-ba3de1fb779c.png?v=1689761697","url":"https:\/\/danabiosci.com\/products\/new-product-284489","provider":"Dana Bioscience","version":"1.0","type":"link"}