{"product_id":"new-product-284224","title":"COUP-TFI polyclonal antibody","description":"\u003cp\u003eChicken ovalbumin upstream promoter transcription factor (COUP-TF) belongs to the NR2 subfamily of the nuclear hormone receptor family. COUP-TFI and COUP-TFII are two of the well-characterized members in the NR2 subfamily. These two members are highly conserved in their two zinc-finger DNA binding domains (DBD) and the ligand binding domain (LBD), and function as repressors or activators of downstream target genes to regulate different biological processes. COUP-TFI and II bind to 5'-AGGTCA-3' motif palindromes, either directly or indirectly, through heterodimer formation with other proteins (e.g. RXRs) to regulate downstream target gene expression. COUP-TFI is involved in neuronal development, tissue patterning, and differentiation. COUP-TFII has been shown to be involved in angiogenesis, glucose homeostasis, and mesenchymal cell commitment.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Pig","offer_id":45809761288472,"sku":"ABCBW12314","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_bfb67a9d-f1f7-4e55-ad59-bf2f38bb3665.png?v=1689761058","url":"https:\/\/danabiosci.com\/products\/new-product-284224","provider":"Dana Bioscience","version":"1.0","type":"link"}