{"product_id":"new-product-284122","title":"PKR (phospho-T446) Rabbit monoclonal antibody","description":"\u003cp\u003eAn interferon-inducible, RNA-dependent protein serine\/threonine kinase (PKR) has been described. PKR in earlier literature is variously known as DAI, dsJ, PI kinase, p65, p67 or TIK for the mouse kinase; and p68 or p69 for the human kinase. The PKR kinase substrate is the α subunit of protein synthesis initiation factor eIF-2. Phosphorylation of eIF-2α on serine-51 results in inhibition of translation. Molecular cDNA clones have been isolated from both human and mouse cells. The serine\/threonine kinase catalytic domains map to the carboxy terminal half of the protein while the RNA-binding domains are located in the amino terminal region. Three kinds of regulation of PKR enzymatic activity have been described.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human","offer_id":45809723932952,"sku":"ABCBW12212","price":448.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_a2509269-1d0e-4b8e-b71b-e800e4b2b18d.png?v=1689760826","url":"https:\/\/danabiosci.com\/products\/new-product-284122","provider":"Dana Bioscience","version":"1.0","type":"link"}