{"product_id":"new-product-284086","title":"Rb (phospho-S807) Rabbit monoclonal antibody","description":"\u003cp\u003eThe retinoblastoma tumor suppressor gene product, known as Rb or pRb, regulates differentiation, apoptosis and cell cycle control by coordinating the cell cycle, at G1\/S, with transcriptional machinery that includes the heterodimeric E2F family. During G1, cyclin D (D1, 2, 3)-dependent kinase-mediated phosphorylation of Rb at Ser 795 marks the conversion of Rb from a transcriptionally repressive, hypophosphorylated state to an inactive, phosphorylated state, which may be sustained through mitosis by differential phosphorylation of up to 16 putative serine or threonine residues, including Ser 249\/Thr 252, Thr 373, Thr 356, Ser 780, Ser 807\/Ser 811 and Thr 821\/Thr 826.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":45809708269848,"sku":"ABCBW12176","price":448.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_8d56ac9b-4056-45a0-afb2-d772f83c7389.png?v=1689760740","url":"https:\/\/danabiosci.com\/products\/new-product-284086","provider":"Dana Bioscience","version":"1.0","type":"link"}