{"product_id":"new-product-284082","title":"SCARB1 Rabbit monoclonal antibody","description":"\u003cp\u003eThe macrophage class A scavenger receptors (SR-A) type I and II mediate the uptake of modified low density lipoprotein (LDL), while the scavenger receptor class B type 1 (SR-B1) mediates the selective uptake of cholesterol and cholesterol esters (CE) from HDLs into cells. SREC, Ox-LDL-R1, SR-A and SR-B1 may all be involved in the early development of atherosclerosis. SR-B1, an integral membrane protein, acts as a receptor for various ligands, including apoptotic cells, cholesterol ester, phospholipids, lipoproteins and phosphatidyl-serine. SR-B1, which may be involved in phagocytosis of apoptotic cells, enables the movement of cholesterol between the cell surface and extracellular donors and acceptors. Although it is widely expressed, SR-B1 localizes primarily to cholesterol and sphingomyelin-enriched domains within the plasma membrane, called caveolae.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":45809704010008,"sku":"ABCBW12172","price":448.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_bdad1ecf-5364-42e2-b051-9915083045dd.png?v=1689760732","url":"https:\/\/danabiosci.com\/products\/new-product-284082","provider":"Dana Bioscience","version":"1.0","type":"link"}