{"product_id":"new-product-283293","title":"NLRP3 polyclonal antibody","description":"\u003cp\u003eCryopyrin interacts selectively with apoptosis-associated specklike protein containing a CARD domain (ASC). This complex may function as an upstream activator of NFkB signaling and caspase-1 activation. The complex also inhibits TNFa induced activation and nuclear translocation of RelA\/NFkB p65. Mutations in Cryopyrin and Pyrin proteins are responsible for several autoinflammatory disorders in humans, including familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS) and chronic infantile neurologic cutaneous and articular syndrome (CINCA).\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human, Mouse, Rat","offer_id":45809414013208,"sku":"ABCBW11383","price":448.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_d1d4671c-8974-4efd-98ab-ea6d68367319.png?v=1689758835","url":"https:\/\/danabiosci.com\/products\/new-product-283293","provider":"Dana Bioscience","version":"1.0","type":"link"}