{"product_id":"new-product-282131","title":"ALS2 polyclonal antibody","description":"\u003cp\u003eThe protein encoded by this gene contains an ATS1\/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse","offer_id":45809159340312,"sku":"ABCBW10221","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_fb1b57d9-119a-4fb9-bc06-a48762b000e5.png?v=1689756043","url":"https:\/\/danabiosci.com\/products\/new-product-282131","provider":"Dana Bioscience","version":"1.0","type":"link"}