{"product_id":"new-product-280588","title":"DNAJB12 polyclonal antibody","description":"\u003cp\u003eActs as a co-chaperone with HSPA8\/Hsc70; required to promote protein folding and trafficking, prevent aggregation of client proteins, and promote unfolded proteins to endoplasmic reticulum-associated degradation (ERAD) pathway. Acts by determining HSPA8\/Hsc70's ATPase and polypeptide-binding activities. Can also act independently of HSPA8\/Hsc70: together with DNAJB14, acts as a chaperone that promotes maturation of potassium channels KCND2 and KCNH2 by stabilizing nascent channel subunits and assembling them into tetramers. While stabilization of nascent channel proteins is dependent on HSPA8\/Hsc70, the process of oligomerization of channel subunits is independent of HSPA8\/Hsc70.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":45808705011992,"sku":"ABCBW08678","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_ae63a990-359e-41c9-94c8-c2529e0e447b.png?v=1689752426","url":"https:\/\/danabiosci.com\/products\/new-product-280588","provider":"Dana Bioscience","version":"1.0","type":"link"}