{"product_id":"new-product-280253","title":"PIH1D1 polyclonal antibody","description":"\u003cp\u003eNop17 (nucleolar protein 17), also known as PIH1D1, is a phylogenetically conserved protein essential for efficient processing of pre-rRNA through its association with a class of small nucleolar RNAs (snoRNAs) during ribosomal biogenesis. SnoRNAs are associated in ribonucleoprotein particles localized to the nucleolus. Nop17 is a 290 amnio acid unstable protein that is stabilized through an interaction with HSP 90α\/β. Nop17 interacts with a core box C\/D snoRNP protein Nop58, indicating a function of Nop17 in mediating the nucleolar retention or proper assembly of the box C\/D snoRNP. A mutation in NOP17 gene may lead to a temperature-sensitive phenotype along with delocalization of key Nop proteins that are essential for snoRNP assembly.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human","offer_id":45808604414232,"sku":"ABCBW08343","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_c5c7b997-da5b-4eff-8c14-aabf29a0e906.png?v=1689751606","url":"https:\/\/danabiosci.com\/products\/new-product-280253","provider":"Dana Bioscience","version":"1.0","type":"link"}