{"product_id":"new-product-280173","title":"ABI3BP polyclonal antibody","description":"\u003cp\u003eTARSH [ABI family, member 3 (NESH) binding protein], whose alternative names include target of Nesh-SH3, Nesh-binding protein, ABI gene family member 3-binding protein, NESHBP, FLJ41743, FLJ41754 or ABI3BP, is a 1,075 amino acid protein involved in cellular senescence and tumor suppression. Loss of TARSH expression may play a role in the pathogenesis of cancer, especially in thyroid and lung. TARSH acts as a signal transduction molecule and is presumed to interact with with Abi-3, a protein involved in inhibition of ectopic metastasis of tumor cells. TARSH is expressed in brain, lung, heart, liver, placenta, pancreas and kidney, and four TARSH isoforms exist as a result of alternative splicing. TARSH contains a SH3 binding motif and a nuclear targeting sequence.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human","offer_id":45808574759192,"sku":"ABCBW08263","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_c396f65c-0df5-451c-a4b3-466585b3b0b5.png?v=1689751399","url":"https:\/\/danabiosci.com\/products\/new-product-280173","provider":"Dana Bioscience","version":"1.0","type":"link"}