{"product_id":"new-product-279756","title":"JMJD8 polyclonal antibody","description":"\u003cp\u003eJMJD8 (Jumonji domain-containing protein 8) is a 334 amino acid protein that contains one Jumonji domain and is expressed as 3 isoforms produced by alternative splicing. The gene that encodes JMJD8 maps to human chromosome 16, which encodes over 900 genes in approximately 90 million base pairs, making up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16 through the CREBBP gene, which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn’s disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":45808482025752,"sku":"ABCBW07846","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_0bb1b9fe-422d-4fcf-b9d1-28e367be4ce2.png?v=1689750325","url":"https:\/\/danabiosci.com\/products\/new-product-279756","provider":"Dana Bioscience","version":"1.0","type":"link"}