{"product_id":"new-product-278391","title":"DDX58 polyclonal antibody","description":"\u003cp\u003eRetinoic acid inducible gene I (RIG-I) is a 925 amino acid, interferon-inducible cellular DExD\/H box RNA helicase that activates type I interferon (IFN), an important effector of the innate immune system that is sensitive to these dsRNA viruses. dsRNA is normally present in very low quantities in cells, so when a virus is present, the elevated levels of dsRNA act as a sign telling RIG-I to activate the production of IFN. RIG-I does this by using its helicase domain to bind to viral dsRNA, thus transmitting the activation signal for IFN through IkB kinase-related kinases and inducing IFN expression.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human","offer_id":45806893367576,"sku":"ABCBW06481","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_3e8754dc-2d4f-4026-a156-9b0e175f3bd2.png?v=1689747066","url":"https:\/\/danabiosci.com\/products\/new-product-278391","provider":"Dana Bioscience","version":"1.0","type":"link"}