{"product_id":"new-product-278290","title":"SLAMF1 polyclonal antibody","description":"\u003cp\u003eFollowing occupancy of the T cell receptor by antigen, T cell proliferation and lymphokine production are determined by a second costimulatory signal delivered by a ligand expressed on antigen-presenting cells. SLAM (for signaling lymphocyte-activation molecule, also designated CDw150) is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. SAP (for SLAM-associated protein) contains an SH2 domain and functions to inhibit SH-PTP2 recruitment to the SLAM docking site, an activity induced by Fyn phosphorylation of SLAM. Mutations of the SAP gene may be associated with X-linked lympho-proliferative disease (XLP)\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse","offer_id":45806802895128,"sku":"ABCBW06380","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_a4ba8deb-4bd8-49b8-9650-e91979158578.png?v=1689746835","url":"https:\/\/danabiosci.com\/products\/new-product-278290","provider":"Dana Bioscience","version":"1.0","type":"link"}