{"product_id":"new-product-278283","title":"PRG2 polyclonal antibody","description":"\u003cp\u003eThe eosinophil major basic protein (EMBP), also designated MBP, PRG2, proteoglycan 2, BMPG, or bone marrow natural killer cell activator, is a constituent of the crystalline core of the eosinophil granule. High levels of the pro-EMBP are present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A\u003cbr\u003e\n(PAPPA), angiotensinogen (AGT) and C3δγ. EMBP may influence antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and may play a role in immune hypersensitivity reactions. EMBP stimulates an Src kinase-dependent activation of class I (A) phosphoinositide 3-kinase and, in turn, activation of protein kinase C ζ in neutrophils. EMBP transcription is under regulation by novel combinatorial interactions of GATA-1, PU.1, and C\/EBPε isoforms.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human, Mouse","offer_id":45806796407064,"sku":"ABCBW06373","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_9a676dcd-9716-44c9-9a2b-96997c48cd51.png?v=1689746821","url":"https:\/\/danabiosci.com\/products\/new-product-278283","provider":"Dana Bioscience","version":"1.0","type":"link"}