{"product_id":"new-product-277881","title":"Smad7 polyclonal antibody","description":"\u003cp\u003eThe protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":45806579843352,"sku":"ABCBW05971","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_4b1b8b22-68de-4eca-8c12-b48ded7b6a19.png?v=1689745855","url":"https:\/\/danabiosci.com\/products\/new-product-277881","provider":"Dana Bioscience","version":"1.0","type":"link"}