{"product_id":"new-product-277588","title":"DUSP10 Polyclonal Antibody","description":"\u003cp\u003eMitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and\/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK\/ERK, SAPK\/JNK and p38. MKP-5 preferentially binds to p38, but also to SAPK\/JNK. It is ubiquitously expressed and localizes to both the cytoplasm and the nucleus. MKP-5 has been implicated in cell proliferation and apoptosis, tumor invasion and immune responses.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,","offer_id":45806490616088,"sku":"ABCBW05678","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_6f20255a-87a5-42b1-80fa-183b4ea56570.png?v=1689745127","url":"https:\/\/danabiosci.com\/products\/new-product-277588","provider":"Dana Bioscience","version":"1.0","type":"link"}