{"product_id":"new-product-276848","title":"Bim polyclonal antibody","description":"\u003cp\u003ePro-apototic Bcl-2 family members promote cell death by neutralizing their anti-apoptotic relatives, which otherwise maintain cell viability by regulating caspase activity. Bim belongs to the BH3-only subgroup of Bcl-2 related proteins, and exists in three distinct isoforms, BimS (short), BimL (long) and BimEL (extra long). ERK1\/2 phosphorylates BimEL, resulting in rapid degradation of the isoform via the proteasome pathway. At least three sites for ERK1\/2 phosphorylation exist on BimEL, whereas ERK1\/2 does not effect BimS and BimL, implying a unique role for BimEL in cell survival signaling\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse","offer_id":45806073938200,"sku":"ABCBW04938","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_1373687e-e015-45ed-9d03-54ea3ae52277.png?v=1689743356","url":"https:\/\/danabiosci.com\/products\/new-product-276848","provider":"Dana Bioscience","version":"1.0","type":"link"}