{"product_id":"new-product-276530","title":"CD116 polyclonal antibody","description":"\u003cp\u003eThe human IL-3, IL-5 and GM-CSF receptors are each composed of both unique a subunits and a common β subunit. The a subunits are low affinity ligand binding proteins while the β subunits do not themselves bind ligand, but are required for high affinity binding by the a subunits. In contrast, the mouse IL-3 receptor has two distinct β subunits, one that functions only in IL-3 mediated cell signaling and a second that is shared with IL-5 and GM-CSF. The murine β-subunits are 91% homologous at the amino acid level but only 56% homologous to the human β subunit. Although neither the murine nor the human β subunit contains tyrosine kinase domains, both activate tyrosine phosphorylation mediated signaling pathways.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Rat","offer_id":45805742653720,"sku":"ABCBW04620","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_02e6393d-22a5-4de8-896e-799129861917.png?v=1689742582","url":"https:\/\/danabiosci.com\/products\/new-product-276530","provider":"Dana Bioscience","version":"1.0","type":"link"}