{"product_id":"new-product-276441","title":"GPR188 polyclonal antibody","description":"\u003cp\u003eThe S-100 protein family consists of a group of calcium-binding proteins that are exclusively expressed in vertebrates and exhibit cell and tissue-specific expression. The expression levels of its members differ in various pathological conditions. The extracellular functions of the S-100 family may include the ability to enhance neurite outgrowth, involvement in inflammation and motility of tumor cells. S-100Z (S100 calcium-binding protein Z) is a 99 amino acid protein that shares 57% and 52% sequence identity with S-100A1 and S-100P, respectively. A dimeric, predominantly α-helical protein, S-100Z contains two EF-hand domains capable of binding calcium ions. Binding of calcium results in conformational changes and exposure of hydrophobic surfaces on the protein. S-100Z interacts with S-100P, and demonstrates highest level of expression in spleen and leukocytes. The S-100Z gene is conserved in chimpanzee, bovine, mouse, rat, chicken and zebrafish, and maps to human chromosome 5q13.3.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human","offer_id":45805654638872,"sku":"ABCBW04531","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_12daea6d-8be0-4ab3-a682-1e0b64c95e29.png?v=1689742377","url":"https:\/\/danabiosci.com\/products\/new-product-276441","provider":"Dana Bioscience","version":"1.0","type":"link"}