{"product_id":"new-product-276398","title":"GPR146 polyclonal antibody","description":"\u003cp\u003eMsx homeobox genes encode for transcription factors that control morphogenesis and are expressed at sites of epithelial-mesenchymal interaction during embryogenesis, such as the Tooth. Two of these genes, Msx-1 and Msx-2, are key factors for the development of tooth and craniofacial skeleton. Msx-1 also down-regulates a master gene of skeletal cells differentiation. Msx-1 and Msx-2 contribute to the initial patterning of dentition as well as playing a pivotal role in terminal cell differentiation. In addition, Msx-1 and Msx-2 are expressed in the epidermis, hair follicles and fibroblasts of the developing fetal skin. In adult skin, Msx-1 and Msx-2 expression is confined to epithelially derived structures. Msx-2 is detected as a diffuse cytoplasmic signal in fetal epidermis and portions of the hair follicle and dermis, but is localized to the nucleus in the adult epidermis. Msx-1 and Msx-2 are also expressed during critical developmental stages of neural tube and neuralcrest, suggesting that these genes play an important role in organogenesis.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Rat,Mouse","offer_id":45805606175000,"sku":"ABCBW04488","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_5cb59862-37bc-4acc-9625-462dfabea10a.png?v=1689742272","url":"https:\/\/danabiosci.com\/products\/new-product-276398","provider":"Dana Bioscience","version":"1.0","type":"link"}