{"product_id":"new-product-276393","title":"GPR141 polyclonal antibody","description":"\u003cp\u003eGrowth\/differentiation factors (GDFs) are members of the TGF superfamily. Members of the TGF superfamily are involved in embryonic development and adult tissue homeostasis. GDF-1 expression is almost exclusively restricted to the central nervous system and mediates cell differentiation events during embryonic development. Neither GDF-3 (Vgr-2) nor GDF-9 contains the conserved cysteine residue which is found in most other TGF superfamily members. GDF-3 is detectable in bone marrow, spleen, thymus and adipose tissue, whereas GDF-9 has only been detected in ovary. GDF-5 (also designated CDMP-1) has been shown to induce activation of plasminogen activator, thereby inducing angiogenesis. It is predominantly expressed in long bones during fetal embryonic development and is involved in bone formation. GDF-5 mutations have been identified in mice with the mutation brachypodism (bp), a mutation which affects the length and number of bones in limbs. GDF-6 and GDF-7 are closely related to GDF-5. GDF-8 has been shown to be a negative regulator of skeletal muscle mass.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human","offer_id":45805602930968,"sku":"ABCBW04483","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_61f9443e-1ec4-449d-b4e3-60563b6bb043.png?v=1689742262","url":"https:\/\/danabiosci.com\/products\/new-product-276393","provider":"Dana Bioscience","version":"1.0","type":"link"}