{"product_id":"new-product-276368","title":"DKK3 polyclonal antibody","description":"\u003cp\u003eDickkopf-related protein 3, antagonizes canonical Wnt signaling by inhibiting LRP5\/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5\/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":45805571932440,"sku":"ABCBW04458","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_57026f79-3613-40ce-9d27-1e8cb0fff3bc.png?v=1689742200","url":"https:\/\/danabiosci.com\/products\/new-product-276368","provider":"Dana Bioscience","version":"1.0","type":"link"}