{"product_id":"new-product-276245","title":"CD248 polyclonal antibody","description":"\u003cp\u003eTumor endothelial marker 1 (TEM1\/endosialin) is a heavily glycosylated, type I transmembrane C-type lectin-like receptor of the Ras superfamily expressed in the vascular endothelium and on fibroblast-like cells in developing organs. Expression of TEM1 largely disappears in adulthood. TEM1 is structurally related to thrombomodulin and complement receptor C1qRp. It consists of three EGF-like domains, a C-type lectin domain and a Sushi domain. TEM1 is highly upregulated in tumor endothelium and is known to function in tumor growth and progression. For this reason TEM1 is a major target in anti-angiogenic tumor therapy. TEM1 may be responsible for concentrating liposomes on the surface of target cells and promoting their fusion with the cell membrane.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human","offer_id":45805456294168,"sku":"ABCBW04335","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_62938587-0c35-4664-96dc-f26ead551b3b.png?v=1689741923","url":"https:\/\/danabiosci.com\/products\/new-product-276245","provider":"Dana Bioscience","version":"1.0","type":"link"}