{"product_id":"new-product-276223","title":"SERPINB1 polyclonal antibody","description":"\u003cp\u003eThe serine proteinase inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions, including the control of blood coagulation, complement activation, programmed cell death and development. Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. The monocyte\/neutrophil elastase inhibitor gene, SERPINB1, belongs to the Ov-serpin family (ovalbuminrelated serpins). Human SerpinB1, also designated monocyte\/neutrophil elastase inhibitor (M\/NEI) or leukocyte elastase inhibitor (LEI), is a cytoplasmic protein which acts as a fast-acting stoichiometric proteinase inhibitor that regulates the activity of neutrophil elastase (NE), cathepsin-G and proteinase-3. There are four homologous genes in mouse designated SerpinB1a, SerpinB1b, SerpinB1c and the pseudogene, Serpinb1-ps1. The three protein-coding genes share significant sequence identity, however SerpinB1a (also designated EIA) has been characterized as the functional ortholog of human SerpinB1.\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Human,Rat,Mouse","offer_id":45805436010776,"sku":"ABCBW04313","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_8ebfc144-2dce-4167-8265-f45ee22c9120.png?v=1689741860","url":"https:\/\/danabiosci.com\/products\/new-product-276223","provider":"Dana Bioscience","version":"1.0","type":"link"}